Persistent airway inflammation and mucus hypersecretion may predispose to mucus plugging and bronchial wall thickening and destruction, resulting in impaired lung function. None of the funding sources had any role in the study.īronchiectasis has been recognized as a debilitating disease with which patients frequently suffer from chronic cough, sputum production and recurrent infective exacerbations. All other authors declared no potential conflict of interest. Zhong and Chen declared that they had received Changjiang Scholars and Innovative Research Team in University ITR0961, The National Key Technology R&D Program of the 12th National Five-year Development Plan 2012BAI05B01 and National Key Scientific & Technology Support Program: Collaborative innovation of Clinical Research for chronic obstructive pulmonary disease and lung cancer No. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: Profs. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: This work received funding from Changjiang Scholars and Innovative Research Team in University ITR0961, The National Key Technology R&D Program of the 12th National Five-year Development Plan 2012BAI05B01 and National Key Scientific & Technology Support Program: Collaborative innovation of Clinical Research for chronic obstructive pulmonary disease and lung cancer No.

Received: MaAccepted: OctoPublished: November 18, 2014Ĭopyright: © 2014 Guan et al. PLoS ONE 9(11):Įditor: Hong-Long (James) Ji, University of Texas Health Science Center at Tyler, United States of America (2014) Characterization of Lung Function Impairment in Adults with Bronchiectasis. Citation: Guan W-j, Gao Y-h, Xu G, Lin Z-y, Tang Y, Li H-m, et al.

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